Increased risk of COVID-19 mortality rate in IFITM3 rs6598045 G allele carriers infected by SARS-CoV-2 delta variant.

doi:10.1186/s40246-022-00434-8

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Article

Increased risk of COVID-19 mortality rate in IFITM3 rs6598045 G allele carriers infected by SARS-CoV-2 delta variant.

Human genomics - 19 Nov 2022

Gholami Melika, Sakhaee Fatemeh, Sotoodehnejadnematalahi Fattah, Zamani Mohammad Saber, Ahmadi Iraj, Anvari Enayat, Fateh Abolfazl

Abstract excerpt

BACKGROUND: The interferon-induced transmembrane-protein 3 (IFITM3) is a vital component of the immune system's defense against viral infection. Variants in the IFITM3 gene have been linked to changes in expression and the risk of severe Coronavirus disease 2019 (COVID-19). This study aimed to investigate whether IFITM3 rs6598045, quantitative polymerase chain reaction (qPCR) cycle threshold (Ct) values, and...

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Identifiers

PMID: 36403064
DOI: 10.1186/s40246-022-00434-8
PMCID: PMC9675951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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