Article
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress.
EMBO reports - 9 Jan 2023
Lagage Valentine, Chen Victor, Uphoff Stephan
Abstract excerpt
Understanding the interplay between phenotypic and genetic adaptation is a focus of evolutionary biology. In bacteria, the oxidative stress response prevents mutagenesis by reactive oxygen species (ROS). We hypothesise that the stress response dynamics can therefore affect the timing of the mutation supply that fuels genetic adaptation to oxidative stress. We uncover that sudden hydrogen peroxide stress causes a...
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