Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SphK-produced S1P in somatic cells is indispensable for LH-EGFR signaling-induced mouse oocyte maturation

17 Nov 2022

Abstract excerpt

Germ cell division and differentiation require intimate contact and interaction with the surrounding somatic cells. Luteinizing hormone (LH) triggers epidermal growth factor (EGF)-like growth factors to promote oocyte maturation and developmental competence by activating EGF receptor (EGFR) in somatic cells. Here, we showed that LH-EGFR signaling-activated sphingosine kinases (SphK) in somatic cells. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36396932
DOI: 10.1038/s41419-022-05415-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SphK-produced S1P in somatic cells is indispensable for LH-EGFR signaling-induced mouse oocyte maturationPMID 36396932Read ↗

SphK-produced S1P in somatic cells is indispensable for LH-EGFR signaling-induced mouse oocyte maturationSemantic proximity Read ↗

MAPKs signaling is obligatory for male reproductive function in a development-specific mannerSemantic proximity Read ↗

SP1 governs primordial folliculogenesis by regulating pregranulosa cell development in miceSemantic proximity Read ↗

Asynchronous embryonic germ cell development leads to a heterogeneity of postnatal ovarian follicle activation and may influence the timing of puberty onset in miceSemantic proximity Read ↗

Significance of epidermal growth factor receptor signaling for acquisition of meiotic and developmental competence in mammalian oocytes†Semantic proximity Read ↗

Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish OvarySemantic proximity Read ↗

Characterization of FSH signalling networks in bovine cumulus cells: a perspective on oocyte competence acquisitionSemantic proximity Read ↗

Epidermal growth factor receptor signaling uncouples germ cells from the somatic follicular compartment at ovulationSemantic proximity Read ↗

Stem cell factor (SCF)-kit mediated phosphatidylinositol 3 (PI3) kinase signaling during mammalian oocyte growth and early follicular development.Semantic proximity Read ↗

Extracellular vesicles from iPSC-MSCs alleviate chemotherapy-induced mouse ovarian damage via the ILK-PI3K/AKT pathwaySemantic proximity Read ↗

The epidermal growth factor network: role in oocyte growth, maturation and developmental competenceSemantic proximity Read ↗

Ubiquitin–proteasome pathway modulates mouse oocyte meiotic maturation and fertilization via regulation of MAPK cascade and cyclin B1 degradationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.