Article

Exploration of New Nickel and Copper(II) Complexes as Potential P53/Caspase 9 Activator in Human Colon Cancer Cell Line

2022-10-01

Abstract excerpt

Abstract The two new complexes, namely [NiU2(H2O)2]SO4, (NiU) and [CuU2(H2O)2]SO4, (CuU) [U = 5,6-diamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione monohydrate] were synthesized and characterized by elemental analysis, physicochemical, spectroscopic, (UV-visible, IR, ESI-MS, and XRD), thermal analysis and cyclic voltametric techniques. As showed in the data obtained, an octahedral geometry has been assigned for the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 33dd2995-d014-5351-a48b-a2518818e40a
DOI: 10.1134/s1070363222100206

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exploration of New Nickel and Copper(II) Complexes as Potential P53/Caspase 9 Activator in Human Colon Cancer Cell LineDOI 10.1134/s1070363222100206Read

Unravelling the Anticancer Potential of a Square Planar Copper Complex: Toward Non-platinum ChemotherapySemantic proximity Read

Influence of cobalt (III) Schiff base complexes on in-vitro anti-proliferative, oxidative stress and gene expression analysis in HeLa and HepG2 cell linesSemantic proximity Read

Cytotoxic, pro-apoptotic, pro-oxidant, and non-genotoxic activities of a novel copper(II) complex against human cervical cancerSemantic proximity Read

Copper Complexes as Anticancer AgentsSemantic proximity Read

Copper(II) Phenanthroline-Based Complexes as Potential AntiCancer Drugs: A Walkthrough on the Mechanisms of ActionSemantic proximity Read

Progress of Metal‐Based Anticancer Chemotherapeutic Agents in Last two Decades and their Comprehensive Biological (DNA/RNA Binding, Cleavage and Cytotoxicity Activity) StudiesSemantic proximity Read

Mechanistic insights into a novel chromone-appended Cu( ii ) anticancer drug entity: in vitro binding profile with DNA/RNA substrates and cytotoxic activity against MCF-7 and HepG2 cancer cellsSemantic proximity Read

The inhibitory effects of a new cobalt-based polyoxometalate on the growth of human cancer cellsSemantic proximity Read

Copper Nanoparticles Induce Apoptosis and Oxidative Stress in SW-480 Human Colon Cancer Cell LineSemantic proximity Read

Metal-Based Anticancer Complexes and p53: How Much Do We Know?Semantic proximity Read

In vitro anticancer activity of hydrogen sulfide and nitric oxide alongside nickel nanoparticle and novel mutations in their genes in CRC patients.Semantic proximity Read

Organoruthenium metallocycle induced mutation in gld-1 tumor suppression gene in JK1466 strain and appreciable lifespan expansion.Semantic proximity Read