Article
Lipoprotein(a) levels in children with suspected familial hypercholesterolaemia: a cross-sectional study.
European heart journal - 21 Apr 2023
de Boer Lotte M, Hutten Barbara A, Zwinderman Aeilko H, Wiegman Albert
Abstract excerpt
AIMS: Familial hypercholesterolaemia (FH) predisposes children to the early initiation of atherosclerosis and is preferably diagnosed by DNA analysis. Yet, in many children with a clinical presentation of FH, no mutation is found. Adult data show that high levels of lipoprotein(a) [Lp(a)] may underlie a clinical presentation of FH, as the cholesterol content of Lp(a) is included in conventional LDL cholesterol...
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