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Article

Proposal of a familial hypercholesterolemia paediatric diagnostic score (FH-PeDS).

European journal of preventive cardiology - 14 Jul 2026

Kafol Jan, Miranda Beatriz, Sikonja Rok, Sikonja Jaka, Wiegman Albert, Medeiros Ana Margarida, Alves Ana Catarina, Freiberger Tomas, Hutten Barbara A, Mlinaric Matej, Battelino Tadej, Humphries Steve E, Bourbon Mafalda, Groselj Urh

Abstract excerpt

AIMS: Familial hypercholesterolemia (FH) significantly increases cardiovascular risk from childhood yet remains widely underdiagnosed. This cross-sectional study aimed to evaluate existing paediatric FH diagnostic criteria in real-world cohorts and to develop two novel diagnostic tools: a semi-quantitative scoring system (FH-PeDS) and a machine learning model (ML-FH-PeDS) to enhance early FH detection. METHODS...

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Identifiers

PMID: 40578816
DOI: 10.1093/eurjpc/zwaf352
PMCID: PMC13364047

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FH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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