Article
Comparative Analysis of a Developed Probe-Based Real-Time PCR and PCR-SSP for HLA-B*27 Detection among Thai Blood Donors.
Clinical laboratory - 1 Nov 2022
Intharanut Kamphon, Ruanthong Fonthip, Chidtrakoon Sarisa, Nathalang Oytip
Abstract excerpt
BACKGROUND: The human leukocyte antigen (HLA) class I gene, the B locus, allele 27, HLA-B*27 is one of the most fascinating risk factors that is strongly associated with developing spondyloarthropathies (SpA). HLA-B27 testing has been routinely available in the diagnosis of those diseases. This study aimed to develop a fluorogenic real-time PCR and to compare it with PCR-SSP to detect the HLA-B*27 allele among...
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