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What Is Sepsis, Who Gets It, How, and Why? The Keys to Unlocking Precision Medicine in Sepsis.

Critical care medicine - 1 Apr 2026

Gay Elizabeth A, Meyer Nuala J, Sinha Pratik

Abstract excerpt

Due to its nonspecific clinical criteria, sepsis is clinically, microbiologically, pathophysiologically and immunologically highly heterogeneous. Consequently, despite hundreds of clinical trials, no host-targeted therapy has been shown to be ubiquitously efficacious, leading investigators to pursue more precision-based approaches for enriching sepsis populations through the identification of subgroups or...

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Phenotype
Precision Medicine
Sepsis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41575283
DOI: 10.1097/CCM.0000000000007043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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