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Article

BICOSS: Bayesian iterative conditional stochastic search for GWAS.

BMC bioinformatics - 12 Nov 2022

Williams Jacob, Ferreira Marco A R, Ji Tieming

Abstract excerpt

BACKGROUND: Single marker analysis (SMA) with linear mixed models for genome wide association studies has uncovered the contribution of genetic variants to many observed phenotypes. However, SMA has weak false discovery control. In addition, when a few variants have large effect sizes, SMA has low statistical power to detect small and medium effect sizes, leading to low recall of true causal single nucleotide...

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Identifiers

PMID: 36371147
DOI: 10.1186/s12859-022-05030-0
PMCID: PMC9652902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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