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Microglia in Alzheimer's Disease: Exploring How Genetics and Phenotype Influence Risk

9 Feb 2019

Abstract excerpt

Research into the function of microglia has dramatically accelerated during the last few years, largely due to recent genetic findings implicating microglia in virtually every neurodegenerative disorder. In Alzheimer's disease (AD), a majority of risk loci discovered through genome-wide association studies were found in or near genes expressed most highly in microglia leading to the hypothesis that microglia play...

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PMID: 30738892
DOI: 10.1016/j.jmb.2019.01.045

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