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Article

Aberrant expression of KDM1A inhibits ferroptosis of lung cancer cells through up-regulating c-Myc

10 Nov 2022

Abstract excerpt

Ferroptosis is a cell death process caused by metabolic dysfunction with the feature of aberrant iron accumulation. Emerging studies have identified that ferroptosis is an important biological function involving in the tumorigenesis, and targeting ferroptosis could provide promising therapeutic targets for lung cancer. However, such therapeutic strategies show limited therapeutic effect owing to drug resistance...

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PMID: 36357457
DOI: 10.1038/s41598-022-23699-4

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