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Bone morphogenetic proteins, activins, and growth and differentiation factors in tumor immunology and immunotherapy resistance

24 Oct 2022

Abstract excerpt

The TGF-β superfamily is a group of secreted polypeptides with key roles in exerting and regulating a variety of physiologic effects, especially those related to cell signaling, growth, development, and differentiation. Although its central member, TGF-β, has been extensively reviewed, other members of the family-namely bone morphogenetic proteins (BMPs), activins, and growth and differentiation factors...

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PMID: 36353620
DOI: 10.3389/fimmu.2022.1033642

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