Article
CC16 polymorphisms in asthma, asthma subtypes, and asthma control in adults from the Agricultural Lung Health Study.
Respiratory research - 9 Nov 2022
Gribben K C, Wyss A B, Poole J A, Farazi P A, Wichman C, Richards-Barber M, Beane Freeman L E, Henneberger P K, Umbach D M, London S J, LeVan T D
Abstract excerpt
BACKGROUND: The club cell secretory protein (CC16) has anti-inflammatory and antioxidant effects and is a potential early biomarker of lung damage. The CC16 single nucleotide polymorphism (SNP) rs3741240 risk allele (A) has been inconsistently linked to asthma; other tagging SNPs in the gene have not been explored. The aim was to determine whether CC16 tagging polymorphisms are associated with adult asthma,...
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