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Article

Functional connectivity response to acute pain assessed by fNIRS is associated with BDNF genotype in fibromyalgia: an exploratory study.

Scientific reports - 6 Nov 2022

de Oliveira Franco Álvaro, de Oliveira Venturini Guilherme, da Silveira Alves Camila Fernanda, Alves Rael Lopes, Vicuña Paul, Ramalho Leticia, Tomedi Rafaela, Bruck Samara Machado, Torres Iraci L S, Fregni Felipe, Caumo Wolnei

Abstract excerpt

Fibromyalgia is a heterogenous primary pain syndrome whose severity has been associated with descending pain modulatory system (DPMS) function and functional connectivity (FC) between pain processing areas. The brain-derived neurotrophic factor (BDNF) Val66Met single nucleotide polymorphism has been linked to vulnerability to chronic pain. In this cross-sectional imaging genetics study, we investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36336706
DOI: 10.1038/s41598-022-23476-3
PMCID: PMC9637689

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