Article
No relationship between the ins del polymorphism of the serotonin transporter promoter and pain perception in fibromyalgia patients and healthy controls.
European journal of pain (London, England) - 1 Aug 2010
Potvin Stéphane, Larouche Annie, Normand Edith, de Souza Juliana Barcellos, Gaumond Isabelle, Marchand Serge, Grignon Sylvain
Abstract excerpt
BACKGROUND: In animals, decades of research have shown that serotonin (5-HT) is involved in endogenous pain inhibition systems, which are deficient in chronic pain disorders such as fibromyalgia (FM). In humans, there is preliminary evidence showing that 5-HT is involved in the FM pathophysiology. In the current endophenotyping study, we sought to investigate, for the first time in humans, the relationships...
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