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Article

Suppressed prefrontal cortex oscillations associate with clinical pain in fibrodysplasia ossificans progressiva.

Orphanet journal of rare diseases - 30 Jan 2021

Peng Ke, Karunakaran Keerthana Deepti, Labadie Robert, Veliu Miranda, Cheung Chandler, Lee Arielle, Yu Paul B, Upadhyay Jaymin

Abstract excerpt

BACKGROUND: Pain is a highly prevalent symptom experienced by patients across numerous rare musculoskeletal conditions. Much remains unknown regarding the central, neurobiological processes associated with clinical pain in musculoskeletal disease states. Fibrodysplasia ossificans progressiva (FOP) is an inherited condition characterized by substantial physical disability and pain. FOP arises from mutations of the...

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PMID: 33516233
DOI: 10.1186/s13023-021-01709-4
PMCID: PMC7847608

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