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A 1-bp deletion in Mc1r in a Norway rat (Rattus norvegicus) from Sado Island, Japan gives rise to a yellowish color variant: an insight into mammalian MC1R variants.

Genes & genetic systems - 14 Jul 2021

Tsunoi Takeru, Noju Koki, Eto Takeshi, Suzuki Hitoshi

Abstract excerpt

The melanocortin-1 receptor gene (MC1R) controls production of the pigments eumelanin and pheomelanin. Changes in MC1R lead to variation in coat color in mammals, which can range from entirely black (melanism) to yellowish. In this study, we report a case of a wild-caught Norway rat (Rattus norvegicus) from Sado Island, Japan with a yellowish coat color. Upon sequencing the whole coding region of the Mc1r gene...

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Share to Receptor, Melanocortin, Type 1

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Identifiers

PMID: 33994400
DOI: 10.1266/ggs.20-00049

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