Article
Polymorphisms and plasma levels of IL-27: impact on genetic susceptibility and clinical outcome of bladder cancer.
BMC cancer - 27 May 2015
Zhou Bin, Zhang Peng, Tang Tielong, Liao Hong, Zhang Kui, Pu Yan, Chen Peng, Song Yaping, Zhang Lin
Abstract excerpt
BACKGROUND: Interleukin-27 (IL-27) has been recognized as a pleiotropic cytokine with both pro- and anti-inflammatory properties. Few studies have investigated polymorphisms and serum/plasma levels of IL-27 in diseases including cancers. This study has analyzed the associations of IL-27 gene polymorphisms, as well as plasma levels of IL-27, with susceptibility to bladder cancer and clinical outcome. METHODS:...
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