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NFKB1 Gene Mutant Was Associated with Prognosis of Coronary Artery Disease and Exacerbated Endothelial Mitochondrial Fission and Dysfunction.

Oxidative medicine and cellular longevity - 1 Jan 2022

Luo Jun-Yi, Liu Fen, Fang Bin-Bin, Tian Ting, Li Yan-Hong, Zhang Tong, Li Xiao-Mei, Yang Yi-Ning

Abstract excerpt

Endothelial apoptosis is the core pathological change in atherosclerotic cardiovascular disease, including coronary artery disease (CAD). Determining the molecular mechanisms underlying endothelial apoptosis is important. Nuclear factor kappa B (NF-κB) is a crucial transcription factor for controlling apoptosis. Our previous study demonstrated that the -94 ATTG ins/del mutant in the promoter of NFKB1 gene...

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Identifiers

PMID: 36317060
DOI: 10.1155/2022/9494926
PMCID: PMC9617727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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