Article
-94 ATTG insertion/deletion polymorphism of the NFKB1 gene is associated with coronary artery disease in Han and Uygur women in China.
Genetic testing and molecular biomarkers - 1 Jun 2014
Yang Yi-Ning, Zhang Jin-Yu, Ma Yi-Tong, Xie Xiang, Li Xiao-Mei, Liu Fen, Chen Bang-Dang, Dong Xing-Hui, Zheng Ying-Ying, Pan Shuo, Zhai Hui, Li Dong-Ze, Chen Qing-Jie
Abstract excerpt
OBJECTIVES: The nuclear factor kappa-light-chain enhancer of activated B cells (NF-κB) signaling pathway plays a key role in the regulatory network of inflammation. The deletion variant allele of the NFKB1-94 insertion/deletion (ins/del) ATTG promoter polymorphism results in lower transcription levels of the p50 subunit, and the variant allele has been associated with several inflammatory diseases as well as with...
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