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Article

Mutant DD genotype of NFKB1 gene is associated with the susceptibility and severity of coronary artery disease.

Journal of molecular and cellular cardiology - 1 Feb 2017

Luo Jun-Yi, Li Xiao-Mei, Zhou Yun, Zhao Qiang, Chen Bang-Dang, Liu Fen, Chen Xiao-Cui, Zheng Hong, Ma Yi-Tong, Gao Xiao-Ming, Yang Yi-Ning

Abstract excerpt

Nuclear factor κappa B (NF-κB) is an important transcription factor in the development and progression of coronary artery disease (CAD). Recent evidence suggests that -94 ATTG ins/del mutant in the promoter of NFKB1 gene is an essential functional mutant. The present study demonstrated the frequencies of the del/del (DD) genotype and del (D) allele were significantly higher in CAD patients than in controls. CAD...

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Identifiers

PMID: 28088561
DOI: 10.1016/j.yjmcc.2017.01.005

Genes

CAD
NFKB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Mutant DD genotype of NFKB1 gene is associated with the susceptibility and severity of coronary artery disease.PMID 28088561Read ↗

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