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Article

Effect on the conformations of the spike protein of SARS-CoV-2 due to mutation.

Biotechnology and applied biochemistry - 1 Jun 2023

Gupta Aayatti Mallick, Chakrabarti Jaydeb

Abstract excerpt

The spike protein of SARS-CoV-2 mediates receptor binding and cell entry and is the key immunogenic target for virus neutralization and the present attention of many vaccine layouts. It exhibits significant conformational flexibility. We study the structural fluctuations of spike protein among the most common mutations that appeared in the variant of concerns (VOC). We report the thermodynamics of conformational...

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Identifiers

PMID: 36314068
DOI: 10.1002/bab.2413
PMCID: PMC9874481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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