SNP rs9387478 at ROS1-DCBLD1 Locus is Significantly Associated with Lung Cancer Risk and Poor Survival in Indian Population.

doi:10.31557/APJCP.2022.23.10.3553

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Article

SNP rs9387478 at ROS1-DCBLD1 Locus is Significantly Associated with Lung Cancer Risk and Poor Survival in Indian Population.

Asian Pacific journal of cancer prevention : APJCP - 1 Oct 2022

Chongtham Jonita, Pandey Namita, Sharma Lokesh Kumar, Mohan Anant, Srivastava Tapasya

Abstract excerpt

OBJECTIVE: Receptor tyrosine kinases (RTK) are relevant therapeutic targets in the treatment of lung cancer. Germline susceptibility variants that influence these RTKs may provide new insights into their regulation. rs9387478 is located in the genomic interval between two RTK-genes ROS1/DCBLD1, of which ROS1 alterations are implicated in lung carcinogenesis and treatment response while the latter remains poorly...

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PMID: 36308382
DOI: 10.31557/APJCP.2022.23.10.3553
PMCID: PMC9924343

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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