Article
Heterozygous alterations of TNFRSF13B/TACI in tonsillar hypertrophy and sarcoidosis.
Clinical & developmental immunology - 1 Jan 2013
Speletas Matthaios, Salzer Ulrich, Florou Zoe, Petinaki Efthimia, Daniil Zoe, Bardaka Fotini, Gourgoulianis Konstantinos I, Skoulakis Charalampos, Germenis Anastasios E
Abstract excerpt
TNFRSF13B/TACI defects have been associated with CVID pathogenesis and/or phenotype, especially the development of benign lymphoproliferation and autoimmunity. Our purpose was to investigate the role of TNFRSF13B/TACI defects in the pathogenesis of two common lymphoproliferative disorders, namely, sarcoidosis and tonsillar hypertrophy (TH). 105 patients (71 with sarcoidosis and 34 with TH, including 19 without...
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