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Article

Landscape of Genomic Alterations and PD-L1 Expression in Early-Stage Non-Small-Cell Lung Cancer (NSCLC)-A Single Center, Retrospective Observational Study.

International journal of molecular sciences - 19 Oct 2022

Stephan-Falkenau Susann, Streubel Anna, Mairinger Thomas, Kollmeier Jens, Misch Daniel, Thiel Sebastian, Bauer Torsten, Pfannschmidt Joachim, Hollmann Manuel, Wessolly Michael, Blum Torsten Gerriet

Abstract excerpt

Precision oncology and immunotherapy have revolutionized the treatment of advanced non-small-cell lung cancer (NSCLC). Emerging studies show that targeted therapies are also beneficial for patients with driver alterations such as epidermal growth factor receptor (EGFR) mutations in early-stage NSCLC (stages I-IIIA). Furthermore, patients with elevated programmed death-ligand 1 (PD-L1) expression appear to respond...

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Identifiers

PMID: 36293366
DOI: 10.3390/ijms232012511
PMCID: PMC9604339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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