Article
Clinicopathological and molecular characteristics associated with PD-L1 expression in non-small cell lung cancer: a large-scale, multi-center, real-world study in China.
Journal of cancer research and clinical oncology - 1 May 2021
Zheng Qiang, Huang Yan, Zeng Xin, Chen Xiaoyan, Shao Shihong, Jin Yan, Xue Qianqian, Wang Yue, Guo Yan, Gu Bin, Wu Chunyan, Li Yuan
Abstract excerpt
PURPOSE: The study aimed to evaluate the clinicopathological and molecular profiles associated with programmed death ligand 1 (PD-L1) expression in non-small cell lung cell (NSCLC) in a large-scale, multi-center, real-world Chinese cohort. METHODS: A total of 6295 NSCLC specimens from six centers in China were analyzed by PD-L1 (22C3) assay. PD-L1 expression in tumor cells (TCs) was classified as negative (TPS...
Topics
- Adenocarcinoma
- Aged
- Anaplastic Lymphoma Kinase
- B7-H1 Antigen
- Carcinoma, Non-Small-Cell Lung
- China
- ErbB Receptors
- Female
- Gene Expression Regulation, Neoplastic
- Humans