Association of PD-L1 expression with driver gene mutations and clinicopathological characteristics in non-small cell lung cancer: A real-world study of 10 441 patients.

doi:10.1111/1759-7714.15244

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Association of PD-L1 expression with driver gene mutations and clinicopathological characteristics in non-small cell lung cancer: A real-world study of 10 441 patients.

Thoracic cancer - 1 Apr 2024

Ruiz Gonzalo, Enrico Diego, Mahmoud Yamil D, Ruiz Alan, Cantarella María Florencia, Leguina Laura, Barberis Mariana, Beña Asunción, Brest Esteban, Starapoli Solange, Mendoza Bertelli Andrea, Tsou Florencia, Pupareli Carmen, Coppola María Pía, Scocimarro Alejandra, Sena Susana, Levit Patricio, Perfetti Aldo, Aman Enrique, Girotti María Romina, Arrieta Oscar, Martín Claudio, Salanova Rubén

Abstract excerpt

BACKGROUND: Programmed death ligand-1 (PD-L1) expression is a well-known predictive biomarker of response to immune checkpoint blockade in non-small cell lung cancer (NSCLC). However, there is limited evidence of the relationship between PD-L1 expression, clinicopathological features, and their association with major driver mutations in NSCLC patients in Latin America. METHODS: This retrospective study included...

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PMID: 38456253
DOI: 10.1111/1759-7714.15244
PMCID: PMC11016406

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