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Article

Senescence-associated beta-galactosidase is lysosomal beta-galactosidase.

Aging cell - 1 Apr 2006

Lee Bo Yun, Han Jung A, Im Jun Sub, Morrone Amelia, Johung Kimberly, Goodwin Edward C, Kleijer Wim J, DiMaio Daniel, Hwang Eun Seong

Abstract excerpt

Replicative senescence limits the proliferation of somatic cells passaged in culture and may reflect cellular aging in vivo. The most widely used biomarker for senescent and aging cells is senescence-associated beta-galactosidase (SA-beta-gal), which is defined as beta-galactosidase activity dete...

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Identifiers

PMID: 16626397
DOI: 10.1111/j.1474-9726.2006.00199.x

Genes

GLB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16626397-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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