Article
Somatic genetic variation in healthy tissue and non-cancer diseases.
European journal of human genetics : EJHG - 1 Jan 2023
Solís-Moruno Manuel, Batlle-Masó Laura, Bonet Núria, Aróstegui Juan I, Casals Ferran
Abstract excerpt
Somatic genetic variants have been studied for several years mostly concerning cancer, where they contribute to its origin and development. It is also clear that the somatic variants load is greater in aged individuals in comparison to younger ones, pointing to a cause/consequence of the senescence process. More recently, researchers have focused on the role of this type of variation in healthy tissue and its...
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