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Article

High Titer of (S)-Equol Synthesis from Daidzein in Escherichia coli

25 Oct 2022

Abstract excerpt

( S )-Equol is the terminal metabolite of daidzein and plays important roles in human health. However, due to anaerobic inefficiency, limited productivity in ( S )-equol-producing strains often hinders ( S )-equol mass production. Here, a multi-enzyme cascade system was designed to generate a higher ( S )-equol titer. First, full reversibility of the ( S )-equol synthesis pathway was found and a blocking reverse...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36282480
DOI: 10.1021/acssynbio.2c00378

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Research trail→

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High Titer of (S)-Equol Synthesis from Daidzein in Escherichia coliPMID 36282480Read ↗

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