Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility

5 Oct 2022

Abstract excerpt

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has killed over 6 million people and is having a devastating social and economic impact around the world. The rise of new variants of concern (VOCs) represents a difficult challenge due to the loss of vaccine and natural immunity, as well as increased transmissibility. All VOCs contain mutations in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Influenza Virus Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36277437
DOI: 10.3389/fmedt.2022.1009451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibilityPMID 36277437Read ↗

SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibilitySemantic proximity Read ↗

Structural and computational insights into the SARS-CoV-2 Omicron RBD-ACE2 interactionSemantic proximity Read ↗

Assessment of mutations on RBD in the Spike protein of SARS-CoV-2 Alpha, Delta and Omicron variants.Semantic proximity Read ↗

Molecular Insights into the Variability in Infection and Immune Evasion Capabilities of SARS-CoV-2 Variants: A Sequence and Structural Investigation of the RBD Domain.Semantic proximity Read ↗

Structural and computational insights into the SARS-CoV-2 Omicron RBD-ACE2 interactionSemantic proximity Read ↗

Comparative Study of the Mutations Observed in the SARS-CoV-2 RBD Variants of Concern and Their Impact on the Interaction with the ACE2 Protein.Semantic proximity Read ↗

Differential Interactions between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of ConcernSemantic proximity Read ↗

Assessment of Mutations on RBD in the Spike Protein of SARS-CoV-2 Alpha, Delta and Omicron VariantsSemantic proximity Read ↗

Molecular dynamics simulations highlight the altered binding landscape at the spike-ACE2 interface between the Delta and Omicron variants compared to the SARS-CoV-2 original strain.Semantic proximity Read ↗

Molecular dynamics simulations of the delta and omicron SARS-CoV-2 spike – ACE2 complexes reveal distinct changes between both variantsSemantic proximity Read ↗

Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interactionSemantic proximity Read ↗

Mutations on RBD of SARS-CoV-2 Omicron variant result in stronger binding to human ACE2 receptor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.