Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value.

doi:10.1164/rccm.201510-2091OC

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Article

Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value.

American journal of respiratory and critical care medicine - 1 Sept 2016

Farhat Maha R, Sultana Razvan, Iartchouk Oleg, Bozeman Sam, Galagan James, Sisk Peter, Stolte Christian, Nebenzahl-Guimaraes Hanna, Jacobson Karen, Sloutsky Alexander, Kaur Devinder, Posey James, Kreiswirth Barry N, Kurepina Natalia, Rigouts Leen, Streicher Elizabeth M, Victor Tommie C, Warren Robin M, van Soolingen Dick, Murray Megan

Abstract excerpt

RATIONALE: The development of molecular diagnostics that detect both the presence of Mycobacterium tuberculosis in clinical samples and drug resistance-conferring mutations promises to revolutionize patient care and interrupt transmission by ensuring early diagnosis. However, these tools require the identification of genetic determinants of resistance to the full range of antituberculosis drugs. OBJECTIVES: To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26910495
DOI: 10.1164/rccm.201510-2091OC
PMCID: PMC5027209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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