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Article

Defining the extent of gene function using ROC curvature.

Bioinformatics (Oxford, England) - 13 Dec 2022

Fischer Stephan, Gillis Jesse

Abstract excerpt

MOTIVATION: Interactions between proteins help us understand how genes are functionally related and how they contribute to phenotypes. Experiments provide imperfect 'ground truth' information about a small subset of potential interactions in a specific biological context, which can then be extended to the whole genome across different contexts, such as conditions, tissues or species, through machine learning...

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Identifiers

PMID: 36271855
DOI: 10.1093/bioinformatics/btac692
PMCID: PMC9750128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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