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Article

Unifying measures of gene function and evolution.

Proceedings. Biological sciences - 22 Jun 2006

Wolf Yuri I, Carmel Liran, Koonin Eugene V

Abstract excerpt

Recent genome analyses revealed intriguing correlations between variables characterizing the functioning of a gene, such as expression level (EL), connectivity of genetic and protein-protein interaction networks, and knockout effect, and variables describing gene evolution, such as sequence evolution rate (ER) and propensity for gene loss. Typically, variables within each of these classes are positively...

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Identifiers

PMID: 16777745
DOI: 10.1098/rspb.2006.3472
PMCID: PMC1560323

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