Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The risk of colorectal cancer in individuals with mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene: An English population-based study.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 May 2023

Birch Rebecca J, Peckham Daniel, Wood Henry M, Quirke Philip, Konstant-Hambling Rob, Brownlee Keith, Cosgriff Rebecca, Consortium Genomics England Research, Burr Nicholas, Downing Amy

Abstract excerpt

BACKGROUND: Studies have demonstrated a higher risk of developing colorectal cancer (CRC) in individuals with Cystic Fibrosis (CF), and also a potentially increased risk in carriers of cystic fibrosis transmembrane conductance regulator (CFTR) mutations. Life expectancy for those with CF is rising, increasing the number at risk of developing CRC. METHODS: The incidence of CRC amongst individuals with CF was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to Cystic Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to Ion Transport

Share to Mutation

Source

Identifiers

PMID: 36253274
DOI: 10.1016/j.jcf.2022.10.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The risk of colorectal cancer in individuals with mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene: An English population-based study.PMID 36253274Read ↗

Functional variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene are associated with increased risk of colorectal cancer.Semantic proximity Read ↗

CFTR and colorectal cancer susceptibility: an urgent need for further studies.Semantic proximity Read ↗

Cystic Fibrosis, CFTR, and Colorectal Cancer.Semantic proximity Read ↗

CFTR is a tumor suppressor gene in murine and human intestinal cancer.Semantic proximity Read ↗

Cancer risk among patients with cystic fibrosis and their first-degree relatives.Semantic proximity Read ↗

CFTR and Gastrointestinal Cancers: An UpdateSemantic proximity Read ↗

Cancer risk in nontransplanted and transplanted cystic fibrosis patients: a 10-year study.Semantic proximity Read ↗

Estimation of the familial relative risk of cancer by site from a French population based family study on colorectal cancer (CCREF study).Semantic proximity Read ↗

The CFTR Gene Germline Heterozygous Pathogenic Variants in Russian Patients with Malignant Neoplasms and Healthy Carriers: 11,800 WGS Results.Semantic proximity Read ↗

The risk of gastrointestinal malignancies in cystic fibrosis: case report of a patient with a near obstructing villous adenoma found on colon cancer screening and Barrett's esophagus.Semantic proximity Read ↗

Epidemiology of familial adenomatous polyposis in Sweden: changes over time and differences in phenotype between males and females.Semantic proximity Read ↗

The Prevalence of <i>pks<sup>+</sup> E. coli </i>in Cystic FibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.