Article
Cancer risk among patients with cystic fibrosis and their first-degree relatives.
International journal of cancer - 15 Dec 2009
Johannesson Marie, Askling Johan, Montgomery Scott M, Ekbom Anders, Bahmanyar Shahram
Abstract excerpt
Patients with cystic fibrosis (CF) are at increased risk of some cancers. Little is known about the cancer risks among carriers heterozygous for the CF mutation and it is hypothesized this may be associated with reduced cancer risk. Using Swedish general population-based registers, we identified 884 patients with CF from 1968 to 2003 and 3,033 of their first-degree relatives The subjects were followed from birth...
Topics
- Adult
- Aged
- Cohort Studies
- Cystic Fibrosis
- Family
- Fathers
- Female
- Follow-Up Studies
- Genetic Predisposition to Disease
- Heterozygote
- Humans
- Male