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In vitro and in vivo antiviral activity of nucleoside analogue cHPMPC against African swine fever virus replication

14 Oct 2022

Abstract excerpt

African swine fever virus (ASFV) causes a haemorrhagic disease affecting wild boar and domestic pigs which can result in morbidity and fatality rates of up to 100%. ASFV is a large double-stranded DNA virus which replicates predominantly in the cell cytoplasm and codes for its replication and transcription machinery. No vaccine is widely available and control depends on early detection, culling of infected herds...

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PMID: 36252822
DOI: 10.1016/j.antiviral.2022.105433

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