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Article

Genomics of gallbladder cancer: the case for biomarker-driven clinical trial design.

Cancer metastasis reviews - 1 Jun 2016

Sicklick Jason K, Fanta Paul T, Shimabukuro Kelly, Kurzrock Razelle

Abstract excerpt

BACKGROUND AND AIMS: Gallbladder carcinoma is a rare, aggressive malignancy of the biliary tract associated with a poor prognosis. Despite the deployment of targeted therapies that have demonstrated marked survival benefits in many tumor types, traditional cytotoxic chemotherapy has remained the mainstay of treatment for unresectable and metastatic gallbladder cancer. METHODS: Systematic review of ongoing and...

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Source

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Identifiers

PMID: 26857926
DOI: 10.1007/s10555-016-9602-8
PMCID: PMC4912391

Genes

BRAF
EGFR
ERBB2
PBRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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