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Article

Validation of a Computational Phenotype to Identify Acute Brain Dysfunction in Pediatric Sepsis.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies - 1 Dec 2022

Alcamo Alicia M, Barren Gregory J, Becker Andrew E, Hayes Katie, Fitzgerald Julie C, Balamuth Fran, Pennington Jeffrey W, Curley Martha A Q, Tasker Robert C, Topjian Alexis A, Weiss Scott L

Abstract excerpt

OBJECTIVES: To validate a computational phenotype that identifies acute brain dysfunction (ABD) based on clinician concern for neurologic or behavioral changes in pediatric sepsis. DESIGN: Retrospective observational study. SETTING: Single academic children's hospital. PATIENTS: Four thousand two hundred eighty-nine index sepsis episodes. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: An existing...

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PMID: 36214585
DOI: 10.1097/PCC.0000000000003086
PMCID: PMC9722537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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