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Article

Assessment of BRAF V600E (VE1) immunochemistry for the detection of BRAF V600E mutation in non-small cell lung carcinoma cytology specimens.

Cancer cytopathology - 1 Jan 2023

Garcia Ashley, Rivera Rolon Maria Del Mar, Barkoh Bedia, Chen Wei, Luthra Rajyalakhsmi, Roy-Chowdhuri Sinchita

Abstract excerpt

BACKGROUND: Non-small cell lung carcinoma (NSCLC) patients with BRAF V600E-mutated tumors respond to targeted therapy. Testing for BRAF V600E is commonly performed with molecular methods; however, a mutation-specific VE1 antibody clone can provide an alternative testing option using immunohistochemistry (IHC) for practices using single-gene testing and in situations when the specimen is inadequate for molecular...

Topics

Humans
Carcinoma, Non-Small-Cell Lung
Proto-Oncogene Proteins B-raf
Immunochemistry
Retrospective Studies
Antibodies, Monoclonal
Mutation
Lung Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36200799
DOI: 10.1002/cncy.22648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-36200799-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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