Article
Selection Strategies and Practical Application of BRAF V600E-Mutated Non-Small Cell Lung Carcinoma.
Cancer research and treatment - 1 Jul 2022
Hwang Inwoo, Choi Yoon-La, Lee Hyunwoo, Hwang Soohyun, Lee Boram, Yang Hobin, Chelakkot Chaithanya, Han Joungho
Abstract excerpt
PURPOSE: The incidence of BRAF V600E mutation in non-small cell lung carcinoma (NSCLC) is lower than 2%, which poses difficulties in finding legitimate patients for targeted therapy. We investigated the predictive factors pertaining to BRAF V600E and the effectiveness of the VE1 antibody as a screening method for patient selection. MATERIALS AND METHODS: The study was designed into two steps. In a first group,...
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