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Article

Effects of genotype and food on naltrexone exposure in adolescents.

Clinical and translational science - 1 Nov 2022

Stancil Stephani L, Voss Michaela, Nolte Whitney, Tumberger John, Adelman William, Abdel-Rahman Susan

Abstract excerpt

Naltrexone (NTX), an opioid antagonist metabolized by aldo-keto reductase 1C4 (AKR1C4), is prescribed for psychiatric conditions like eating disorders with variable response. Systemic exposure is highly variable in adults, yet no data exist in children. The purpose of this study was to evaluate NTX exposure in adolescents with eating disorders. Adolescents aged 12-21 years with eating disorders underwent postdose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36200172
DOI: 10.1111/cts.13399
PMCID: PMC9652442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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