Article
DNA repair gene (XRCC1 and XPD) polymorphism and risk of primary ovarian failure.
European review for medical and pharmacological sciences - 1 Sept 2022
Kali Z, Cagiran F T, Kirici P, Dogan C, Celik O
Abstract excerpt
OBJECTIVE: DNA repair genes may be related with the onset of primary ovarian failure (POF). The study was planned to investigate whether the polymorphisms in the DNA repair genes modulate the risk of POF. PATIENTS AND METHODS: This prospective study included 25 women diagnosed with POF and 25 healthy controls. The genotyping and allele of XRCC1 and XPD genes were determined by using Polymerase Chain Reaction and...
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