Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA methylation profile in CpG-depleted regions uncovers a high-risk subtype of early-stage colorectal cancer

28 Sept 2022

Abstract excerpt

BACKGROUND: The current risk stratification system defined by clinicopathological features does not identify the risk of recurrence in early-stage (stage I-II) colorectal cancer (CRC) with sufficient accuracy. We aimed to investigate whether DNA methylation could serve as a novel biomarker for predicting prognosis in early-stage CRC patients. METHODS: We analyzed the genome-wide methylation status of CpG loci...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Surgical Treatments
Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36171645
DOI: 10.1093/jnci/djac183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA methylation profile in CpG-depleted regions uncovers a high-risk subtype of early-stage colorectal cancerPMID 36171645Read ↗

DNA methylation-based patterns for early diagnostic prediction and prognostic evaluation in colorectal cancer patients with high tumor mutation burdenSemantic proximity Read ↗

CpG Methylation Signature Predicts Recurrence in Early-Stage Hepatocellular Carcinoma: Results From a Multicenter StudySemantic proximity Read ↗

A panel of DNA methylation signature from peripheral blood may predict colorectal cancer susceptibility.Semantic proximity Read ↗

A panel of DNA methylation signature from peripheral blood may predict colorectal cancer susceptibilitySemantic proximity Read ↗

Integrative Analysis of DNA Methylation and Gene Expression Profiles Identifies Colorectal Cancer-Related Diagnostic Biomarkers.Semantic proximity Read ↗

Combining the DNA methylation markers of circulating tumor cells with immune infiltrating cells to assess recurrence and prognosis and to suggest a therapeutic strategy in stage III-IV colorectal cancerSemantic proximity Read ↗

Genome-wide discovery of circulating cell-free DNA methylation biomarkers for colorectal cancer detectionSemantic proximity Read ↗

Three DNA methylation epigenotypes in human colorectal cancer.Semantic proximity Read ↗

The methylation of <i>SDC2</i> and <i>TFPI2</i> defined three methylator phenotypes of colorectal cancerSemantic proximity Read ↗

A DNA methylation signature for the prediction of tumour recurrence in stage II colorectal cancerSemantic proximity Read ↗

Deconvolution-based cell-type specific DNA methylation-wide and transcriptome-wide association studies identify risk CpG sites and genes associated with colorectal cancer riskSemantic proximity Read ↗

Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChipsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.