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Article

Physical activity and myocardial infarction risk: insights from the global burden of disease study 1990-2021 and Mendelian randomization analysis.

BMC cardiovascular disorders - 23 Dec 2025

Guo Yujie, Zhao Xianghu, Xu Wenyuan, Cheng Changli, Lei Lan, Zhou Meiqi, He Yikang

Abstract excerpt

INTRODUCTION: Ischemic heart disease (IHD), particularly myocardial infarction (MI), ranks as a leading cause of death globally. While studies have associated physical activity (PA) with a decreased risk of MI, the extent of the global IHD burden attributable to LPA and the impact of PA on MI remain uncertain. METHODS: This study accessed data from the Global Burden of Disease (GBD) 2021 and employed Mendelian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41436927
DOI: 10.1186/s12872-025-05453-6
PMCID: PMC12781736

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LPA

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