Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population.

doi:10.1016/j.ajo.2022.09.004

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Article

Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population.

American journal of ophthalmology - 1 Jan 2023

Hanyuda Akiko, Goto Atsushi, Nakatochi Masahiro, Sutoh Yoichi, Narita Akira, Nakano Shiori, Katagiri Ryoko, Wakai Kenji, Takashima Naoyuki, Koyama Teruhide, Arisawa Kokichi, Imoto Issei, Momozawa Yukihide, Tanno Kozo, Shimizu Atsushi, Hozawa Atsushi, Kinoshita Kengo, Yamaji Taiki, Sawada Norie, Iwagami Masao, Yuki Kenya, Tsubota Kazuo, Negishi Kazuno, Matsuo Keitaro, Yamamoto Masayuki, Sasaki Makoto, Tsugane Shoichiro, Iwasaki Motoki

Abstract excerpt

PURPOSE: A meta-analysis suggests a relationship between abnormal glucose metabolism and primary open-angle glaucoma (POAG); however, the causal association between them remains controversial. We therefore conducted a Mendelian randomization (MR) study to assess the causal association between genetically predicted glycemic traits and the risk of POAG. DESIGN: Two-sample MR design. METHODS: We examined the...

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Identifiers

PMID: 36162535
DOI: 10.1016/j.ajo.2022.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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