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Article

Mutational Landscape and Expression of PD-L1 in Patients with Non-Small Cell Lung Cancer Harboring Genomic Alterations of the MET gene.

Targeted oncology - 1 Nov 2022

Fischer Alessa, Bankel Lorenz, Hiltbrunner Stefanie, Rechsteiner Markus, Rüschoff Jan H, Rushing Elisabeth Jane, Britschgi Christian, Curioni-Fontecedro Alessandra

Abstract excerpt

BACKGROUND: Mesenchymal-to-epithelial transition (MET) exon 14 skipping mutations and MET gene amplification occur in 3-5% of non-small cell lung cancer (NSCLC) patients. Tyrosine kinase inhibitors (TKIs) targeting MET alterations have shown promising results in these patients. OBJECTIVE: The aim of this study was to describe the genomic profile, PD-L1 expression and clinicopathological features of MET...

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Identifiers

PMID: 36136211
DOI: 10.1007/s11523-022-00918-6
PMCID: PMC9684265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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