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Article

IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike

5 Sept 2022

Abstract excerpt

The secreted enzyme interleukin four-induced gene 1 (IL4I1) is involved in the negative control of the adaptive immune response. IL4I1 expression in human cancer is frequent and correlates with poor survival and resistance to immunotherapy. Nevertheless, its mechanism of action remains partially unknown. Here, we identified transmembrane serine protease 13 (TMPRSS13) as an immune cell-expressed surface protein...

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PMID: 36131918
DOI: 10.3389/fimmu.2022.982839

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