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Somatic loss of the Y chromosome is associated with arsenic exposure among Bangladeshi men

21 Sept 2022

Abstract excerpt

BACKGROUND: Arsenic exposure increases the risk of several cancers in humans and contributes to genomic instability. Somatic loss of the Y chromosome (LoY) is a potential biomarker of genomic instability and cancer risk. Smoking is associated with LoY, but few other carcinogens have been investigated. We tested the cross-sectional association between arsenic exposure and LoY in leukocytes among genotyped...

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PMID: 36130227
DOI: 10.1093/ije/dyac176

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