Article
KRAS Mutation Variants and Co-occurring PI3K Pathway Alterations Impact Survival for Patients with Pancreatic Ductal Adenocarcinomas.
The oncologist - 9 Dec 2022
Diehl Adam C, Hannan Lindsay M, Zhen David B, Coveler Andrew L, King Gentry, Cohen Stacey A, Harris William P, Shankaran Veena, Wong Kit M, Green Steven, Ng Natasha, Pillarisetty Venu G, Sham Jonathan G, Park James O, Reddi Deepti, Konnick Eric Q, Pritchard Colin C, Baker Kelsey, Redman Mary, Chiorean E Gabriela
Abstract excerpt
BACKGROUND: KRAS variant alleles may have differential biological properties which impact prognosis and therapeutic options in pancreatic ductal adenocarcinomas (PDA). MATERIALS AND METHODS: We retrospectively identified patients with advanced PDA who received first-line therapy and underwent blood and/or tumor genomic sequencing at the University of Washington between 2013 and 2020. We examined the incidence of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.